Department of Pediatric Medicine, Hematology-Oncology
Texas Children's Hospital
6701 Fannin St.14th FloorHouston, TX 77030Get Map & Directions
Director, Bone Tumors Program and Clinical Leader, Musculoskeletal Tumor Clinic - Texas Children's Cancer CenterAssociate Professor, Department of Pediatrics, Section of Oncology-Hematology, Baylor College of Medicine
University of North Carolina at Chapel Hill, Doctor of Medicine, 1993
Children's Hospital of Los Angeles, Pediatrics, 1996
Baylor College of Medicine, Pediatric Hematology Oncology, 2001
Dr. Lisa Wang is Director of the Bone Tumor Program and the Clinical Leader of the Musculoskeletal Tumor Clinic at Texas Children's Cancer Center. Dr. Wang has a special interest in sarcomas, particularly bone sarcomas such as osteosarcoma and Ewing's sarcoma.
Dr. Wang is Director of the Bone Tumor Program (Osteosarcoma Program) at Texas Children's Cancer Center. The Bone Tumor Program brings together clinical and basic science researchers who are commonly investigating various aspects of osteosarcoma (OS) biology and treatment. The Bone Tumor Program promotes advanced research and clinical activities, which center around bone sarcomas, as part of the educational initiatives for hematology-oncology fellows and students.
Dr. Lisa Wang is also the Clinical Leader of the Musculoskeletal Tumor Clinic, an interdisciplinary clinic within the Outpatient Clinic at Texas Children's Cancer Center. The Musculoskeletal Tumor Clinic brings together a team of clinical specialists to decide on management plans for patients with bone tumors. The team includes an orthopedic surgeon, a pediatric oncologist, a pediatric nurse practitioner, a solid tumor fellow, and a social worker, among other caregivers.
Dr. Lisa Wang is a member of the Children's Oncology Group (COG) where she actively participates on the Bone Tumor Committee. Dr. Wang serves as the institutional Principal Investigator for the cooperative group randomized clinical trial for newly diagnosed Ewing's sarcoma patients (AEWS0031). She previously served as the Principal Investigator for the cooperative group trial to treat newly diagnosed OS patients (EURAMOS protocol).
Dr. Lisa Wang's research interests includes the molecular pathogenesis of osteosarcoma. She specifically focuses on the RECQL4 pathway and Rothmund-Thomson syndrome (RTS), a rare, inherited disorder that predisposes affected individuals to developing osteosarcoma. Her research goals include:
Dr. Lisa Wang is a member of the Solid Tumor Programs and the Bone Tumor Program.
Sarcomas, particularly bone sarcomas (osteosarcoma, Ewing's sarcoma)
Molecular pathogenesis of osteosarcomaRothmund-Thomson syndromeRole of RECQL4 pathways in the pathogenesis of osteosarcoma and skeletal development
Pappo, A.S., Russell, H.V., Kornguth, D.G., Nuchtern, J.G., & Wang, L.L. (2008). Ch. 50.2 Cancers of Childhood, Solid Tumors of Childhood. In: DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology, 8th edition. (Eds. Vincent DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg) Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2008: 2043-2083.
Mehollin-Ray, AR, Kozinetz CA, Schlesinger AE, Guillerman RP, Wang LL. Radiographic Abnormalities and Genotype-Phenotype Correlation with RECQL4 Mutation Status in Rothmund-Thomson Syndrome. American Journal of Roentgenology 2008 Aug;191(2):W62-6.
Hicks MJ, Roth J, Kozinetz CA, Wang LL. Clinicopathologic Features of Osteosarcoma in Patients with Rothmund-Thomson Syndrome. Journal of Clinical Oncology 2007; 25:370-375.
Wang, LL. Biology of Osteogenic Sarcoma. Cancer Journal 2005; 11(4): 294-305.
Wang, LL, Chintagumpala, M, Gebhardt, M. Osteosarcoma: Epidemiology, pathogenesis, clinical presentation, diagnosis, and histology. In: UpToDate, Basow, D (Ed), UpToDate, Waltham, MA 2009. Available at http://www.uptodate.com.
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